Evidence-based clinical protocols and decision support tools developed by the NNH team to guide management of common nephrology conditions.
Diagnosis, empiric antibiotic selection, and management of peritoneal dialysis-associated peritonitis based on ISPD guidelines. Includes organism-specific treatment pathways and catheter exit site infection protocols.
Open ProtocolProcedure-specific antibiotic prophylaxis recommendations for PD patients undergoing dental work, colonoscopy, upper endoscopy with PEG, gynecologic procedures, and PD catheter insertion, based on ISPD guidelines.
Open ProtocolESA dose-adjustment calculator for ESKD patients on Aranesp (darbepoetin alfa) or Mircera (methoxy PEG-epoetin beta). Computes projected 28-day hemoglobin change and recommends a new dose level based on a 9×10 hemoglobin/trajectory matrix.
Open ProtocolInteractive stage-based guidance for monitoring and managing calcium, phosphorus, PTH, vitamin D, bone health, and phosphate-lowering therapy in CKD 1–5D, based on the KDIGO 2017 CKD-MBD Guideline Update.
Open ProtocolEvidence-based workflow integrating KDIGO supportive care, Oxford MEST-C risk stratification, and emerging targeted therapies — Nefecon, sparsentan, atrasentan, sibeprenlimab, and iptacopan — with an interactive risk gauge, immunosuppression decision tool, and evidence library.
Open ProtocolEvidence-based workflow for diagnosing and managing gout and hyperuricemia in patients with CKD. Includes urate-lowering therapy selection (allopurinol, febuxostat, pegloticase), CKD-adjusted dosing, target serum urate, acute flare management, and anti-inflammatory prophylaxis during ULT initiation.
Open ProtocolInteractive teaching tools for ICU and dialysis nursing, residents, fellows, APPs, and nephrologists. Visual circuit diagrams, mechanism walkthroughs, and bedside calculators built around evidence-based references.
Interactive teaching tool covering all major continuous renal replacement therapy modalities — SCUF, CVVH, CVVHD, CVVHDF, SLED, HVHF, CPFA, CHP, and CPF-PE. Animated circuit diagrams, diffusion vs convection explainer, prescription parameters with effluent dose and filtration fraction calculators, and pearls/pitfalls for the bedside.
Open EducatorClinician-facing 4-hour sodium mass-balance simulator built on the Edelman equation. Differential dx engine, electrolyte-free water clearance gauge, animated Edelman fraction, target-Na inverse solver, ADH-off scenario explorer, and osmotic demyelination risk in one cockpit.
Open EducatorClinician-facing simulator and teaching tool for acid-base disorders. Step-by-step primary disorder identification, expected-compensation calculators, anion gap and delta-delta analysis, mixed-disorder unmasking, and a urine-electrolyte module for non-anion-gap acidosis. Built on Berend (NEJM 2014) and Adrogué/Madias (JASN 2010).
Open EducatorClinician-facing tool for evaluating and managing uremic pruritus in CKD and dialysis patients. Covers differential diagnosis, severity assessment, and an evidence-based treatment ladder (emollients, gabapentinoids, antihistamines, UVB phototherapy, difelikefalin) with CKD-adjusted dosing.
Open EducatorInteractive teaching modules for hemodialysis nurses, patient care technicians, dialysis unit staff, and the clinicians who train them. In-depth education on dialysis prescription, adequacy, vascular access, and the science behind day-to-day hemodialysis practice.
